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Article

Zika Virus Targeting by Screening Inhibitors against NS2B/NS3 Protease

22 Nov 2019

Abstract excerpt

Zika flavivirus is suspected to cause Guillain-Barre syndrome in adults and microcephaly, along with other congenital abnormalities in infants. Presently, no vaccines or therapeutics are available. Here, we report novel compounds identified by high-throughput virtual screening of Maybridge chemical database and molecular docking studies. We selected viral enzyme NS2B/NS3 serine protease as the therapeutic target...

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Identifiers

PMID: 31886207
DOI: 10.1155/2019/3947245

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