Article
Hypomethylation of HLA-DRB1 and its clinical significance in psoriasis.
Oncotarget - 14 Feb 2017
Zong Wenkai, Ge Yiping, Han Yue, Yang Xueyuan, Li Qi, Chen Min
Abstract excerpt
Increasing evidences indicate that the abnormal DNA methylation is involved in the pathogenesis of psoriasis. A number of SNPs in HLA-DRB1 have been found being associated with the risk of psoriasis, however it is unclear that metylation status within HLA-DRB1 in psoriasis. Here, DNA and RNA were obtained from epidermis of 56 patients with plaque psoriasis and 28 healthy volunteers served as the control group....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.