Article
Retrospective Analysis of Serotype Switching of Vibrio cholerae O1 in a Cholera Endemic Region Shows It Is a Non-random Process.
PLoS neglected tropical diseases - 1 Oct 2016
Karlsson Stefan L, Thomson Nicholas, Mutreja Ankur, Connor Thomas, Sur Dipika, Ali Mohammad, Clemens John, Dougan Gordon, Holmgren Jan, Lebens Michael
Abstract excerpt
Genomic data generated from clinical Vibrio cholerae O1 isolates collected over a five year period in an area of Kolkata, India with seasonal cholera outbreaks allowed a detailed genetic analysis of serotype switching that occurred from Ogawa to Inaba and back to Ogawa. The change from Ogawa to Inaba resulted from mutational disruption of the methyltransferase encoded by the wbeT gene. Re-emergence of the Ogawa...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
