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Article

Whole-genome sequence comparisons reveal the evolution of Vibrio cholerae O1.

Trends in microbiology - 1 Aug 2015

Kim Eun Jin, Lee Chan Hee, Nair G Balakrish, Kim Dong Wook

Abstract excerpt

The analysis of the whole-genome sequences of Vibrio cholerae strains from previous and current cholera pandemics has demonstrated that genomic changes and alterations in phage CTX (particularly in the gene encoding the B subunit of cholera toxin) were major features in the evolution of V. cholerae. Recent studies have revealed the genetic mechanisms in these bacteria by which new variants of V. cholerae are...

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PMID: 25913612
DOI: 10.1016/j.tim.2015.03.010

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