Article
Mutations in the rfbT gene are responsible for the Ogawa to inaba serotype conversion in Vibrio cholerae O1.
Microbiology and immunology - 1 Jan 1993
Ito T, Hiramatsu K, Ohshita Y, Yokota T
Abstract excerpt
In cultures of Vibrio cholerae strains of Ogawa serotype, variant strains which had undergone serotype conversion from Ogawa to Inaba were identified. The rfbT genes cloned from the parent strains were found to produce a 31-kDa protein in the maxicell system, and to cause serotype conversion when introduced into E. coli cells expressing Inaba serotype specificity. On the other hand, rfbT genes cloned from the...
Topics
- Amino Acid Sequence
- Bacterial Proteins
- Base Sequence
- Cloning, Molecular
- Escherichia coli
- Genes, Bacterial
- Molecular Sequence Data
- Mutation
- O Antigens
- Polysaccharides, Bacterial
- Recombinant Proteins