Comparative genomics reveals mechanism for short-term and long-term clonal transitions in pandemic Vibrio cholerae.

doi:10.1073/pnas.0907787106

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Article

Comparative genomics reveals mechanism for short-term and long-term clonal transitions in pandemic Vibrio cholerae.

Proceedings of the National Academy of Sciences of the United States of America - 8 Sept 2009

Chun Jongsik, Grim Christopher J, Hasan Nur A, Lee Je Hee, Choi Seon Young, Haley Bradd J, Taviani Elisa, Jeon Yoon-Seong, Kim Dong Wook, Lee Jae-Hak, Brettin Thomas S, Bruce David C, Challacombe Jean F, Detter J Chris, Han Cliff S, Munk A Christine, Chertkov Olga, Meincke Linda, Saunders Elizabeth, Walters Ronald A, Huq Anwar, Nair G Balakrish, Colwell Rita R

Abstract excerpt

Vibrio cholerae, the causative agent of cholera, is a bacterium autochthonous to the aquatic environment, and a serious public health threat. V. cholerae serogroup O1 is responsible for the previous two cholera pandemics, in which classical and El Tor biotypes were dominant in the sixth and the current seventh pandemics, respectively. Cholera researchers continually face newly emerging and reemerging pathogenic...

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PMID: 19720995
DOI: 10.1073/pnas.0907787106
PMCID: PMC2741270

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