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Article

Hepatic expression of transcription factors affecting developmental regulation of UGT1A1 in the Han Chinese population.

European journal of clinical pharmacology - 1 Jan 2017

Nie Ya-Li, He Hang, Li Jiang-Feng, Meng Xiang-Guang, Yan Liang, Wang Pei, Wang Shu-Jie, Bi Hong-Zheng, Zhang Li-Rong, Kan Quan-Cheng

Abstract excerpt

PURPOSE: Complete or partial inactivity of UGT1A1, the unique enzyme responsible for bilirubin glucuronidation, is commonly associated with hyperbilirubinemia. We investigated the dynamic expression of UGT1A1, and that of the transcription factors (TFs) involved in its developmental regulation, during human hepatic growth in Han Chinese individuals. METHODS: Eighty-eight prenatal, pediatric, and adult liver...

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PMID: 27704169
DOI: 10.1007/s00228-016-2137-7

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PPARA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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