Article
Quantitative trait analysis of polymorphisms in two bilirubin metabolism enzymes to physiologic bilirubin levels in Chinese newborns.
The Journal of pediatrics - 1 Dec 2014
Zhou Youyou, Wang San-Nan, Li Hong, Zha Weifeng, Peng Qianqian, Li Shilin, Chen Ying, Jin Li
Abstract excerpt
OBJECTIVE: To explore the effects of variants in Uridine Diphosphate Glucuronosyl Transferase 1A1 (UGT1A1) and Heme Oxygenase-1 (HMOX1) on daily physiological bilirubin levels and bilirubin changes during the first week after birth in Chinese newborns. Both UGT1A1 and HMOX1 code rate-limiting enzymes in the bilirubin metabolism pathway. STUDY DESIGN: We conducted a retrospective quantitative trait study to...
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