Article
Clinical effect of naturally random allocation to lower systolic blood pressure beginning before the development of hypertension.
Hypertension (Dallas, Tex. : 1979) - 1 Jun 2014
Ference Brian A, Julius Stevo, Mahajan Nitin, Levy Phillip D, Williams Kim Allan, Flack John M
Abstract excerpt
Systolic blood pressure (SBP) rises approximately linearly with age in most societies. The cause of this rise is unclear. We tested the hypothesis that SBP is causally associated with the rate of rise in SBP with age by evaluating the effect of 12 polymorphisms associated with lower SBP on the age-related rate of rise in SBP in a series of meta-regression analyses involving ≤199 477 participants in 63 studies. We...
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