Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Intracellular d-Serine Accumulation Promotes Genetic Diversity via Modulated Induction of RecA in Enterohemorrhagic Escherichia coli.

Journal of bacteriology - 15 Dec 2016

Connolly James P R, Roe Andrew J

Abstract excerpt

We recently discovered that exposure of enterohemorrhagic Escherichia coli (EHEC) to d-serine resulted in accumulation of this unusual amino acid, induction of the SOS regulon, and downregulation of the type III secretion system that is essential for efficient colonization of the host. Here, we have investigated the physiological relevance of this elevated SOS response, which is of particular interest given the...

Topics

Bacteriophages
Enterohemorrhagic Escherichia coli
Escherichia coli Proteins
Gene Expression Regulation, Bacterial
Gene Expression Regulation, Enzymologic
Genetic Variation
Rec A Recombinases
SOS Response, Genetics
Serine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Open in PubMed Open full text

Identifiers

PMID: 27698085
DOI: 10.1128/JB.00548-16
PMCID: PMC5116935

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Intracellular d-Serine Accumulation Promotes Genetic Diversity via Modulated Induction of RecA in Enterohemorrhagic Escherichia coli.PMID 27698085Read ↗

Genomic plasticity of pathogenic Escherichia coli mediates d-serine tolerance via multiple adaptive mechanisms.Semantic proximity Read ↗

D-serine induces distinct transcriptomes in diverse <i>Escherichia coli</i> pathotypesSemantic proximity Read ↗

Heterogeneity in populations of enterohaemorrhagic Escherichia coli undergoing D-serine adaptation.Semantic proximity Read ↗

Serine Deamination as a New Acid Resistance Mechanism in <i>Escherichia coli</i>Semantic proximity Read ↗

The therapeutic potential of D-Serine in reducing expression of the cytopathic genotoxin colibactinSemantic proximity Read ↗

The SOS system.Semantic proximity Read ↗

[Molecular mechanisms of SOS response of E. coli].Semantic proximity Read ↗

Managing the SOS Response for Enhanced CRISPR-Cas-Based Recombineering in E. coli through Transient Inhibition of Host RecA Activity.Semantic proximity Read ↗

The Escherichia coli argW-dsdCXA genetic island is highly variable, and E. coli K1 strains commonly possess two copies of dsdCXA.Semantic proximity Read ↗

Preventing escape and malfunction of recoded cells due to tRNA base changesSemantic proximity Read ↗

Deficiency in L-serine deaminase interferes with one-carbon metabolism and cell wall synthesis in Escherichia coli K-12.Semantic proximity Read ↗

Effects of Stress, Reactive Oxygen Species, and the SOS Response on De Novo Acquisition of Antibiotic Resistance in Escherichia coli.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.