The Escherichia coli argW-dsdCXA genetic island is highly variable, and E. coli K1 strains commonly possess two copies of dsdCXA.

doi:10.1128/JCM.01172-06

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Article

The Escherichia coli argW-dsdCXA genetic island is highly variable, and E. coli K1 strains commonly possess two copies of dsdCXA.

Journal of clinical microbiology - 1 Nov 2006

Moritz Rebecca L, Welch Rodney A

Abstract excerpt

The genome sequences of Escherichia coli pathotypes reveal extensive genetic variability in the argW-dsdCXA island. Interestingly, the archetype E. coli K1 neonatal meningitis strain, strain RS218, has two copies of the dsdCXA genes for d-serine utilization at the argW and leuX islands. Because the human brain contains d-serine, an epidemiological study emphasizing K1 isolates surveyed the dsdCXA copy number and...

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PMID: 17088369
DOI: 10.1128/JCM.01172-06
PMCID: PMC1698345

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