Article
Genomic plasticity of pathogenic Escherichia coli mediates d-serine tolerance via multiple adaptive mechanisms.
Proceedings of the National Academy of Sciences of the United States of America - 8 Sept 2020
O'Boyle Nicky, Connolly James P R, Tucker Nicholas P, Roe Andrew J
Abstract excerpt
The molecular environment of the host can have profound effects on the behavior of resident bacterial species. We recently established how the sensing and response of enterohemorrhagic Escherichia coli (EHEC) to d-serine (d-Ser) resulted in down-regulation of type 3 secretion system-dependent colonization, thereby avoiding unfavorable environments abundant in this toxic metabolite. However, this model ignores a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.