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Article

Peroxisome proliferator-activated receptor gamma signaling in human sperm physiology

1 Jan 2015

Abstract excerpt

Peroxisome proliferator-activated receptor gamma (PPARγ) is a member of the PPARs, which are transcription factors of the steroid receptor superfamily. PPARγ acts as an important molecule for regulating energy homeostasis, modulates the hypothalamic-pituitary-gonadal (HPG) axis, and is reciprocally regulated by HPG. In the human, PPARγ protein is highly expressed in ejaculated spermatozoa, implying a possible...

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PMID: 25851655
DOI: 10.4103/1008-682x.150253

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