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Energy metabolism in mammalian sperm motility

9 Jun 2022

Abstract excerpt

Mammalian sperm, the only cells that achieve their purpose outside their organism of origin, have to swim vigorously within the female reproductive tract to reach an oocyte. Flagellar dyneins drive sperm motility, which accounts for the consumption of high amounts of ATP. The two main ATP-producing metabolic pathways are compartmentalized in sperm: oxidative phosphorylation in the midpiece and glycolysis in the...

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PMID: 35680646
DOI: 10.1002/wsbm.1569

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