Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RNAi-mediated downregulation of cyclin Y to attenuate human breast cancer cell growth

23 Sept 2016

Abstract excerpt

Cyclin Y (CCNY) is a newly identified PFTK1 interacting protein and has been found to be associated with the proliferation and tumorigenesis of human non-small cell lung cancer. In the present study, we analyzed the expression levels of CCNY in 65 cases of breast cancer (BC) tissues and in four BC cell lines, BT-474, MDA-MB-231, T-47D and MCF-7. Lentivirus-mediated short hairpin RNA (shRNA) was employed to knock...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to RNA modifications and cancer
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27666310
DOI: 10.3892/or.2016.5126

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

RNAi-mediated downregulation of cyclin Y to attenuate human breast cancer cell growthPMID 27666310Read ↗

Cell Cycle Protein Cyclin Y Is Associated With Human Non–Small-Cell Lung Cancer Proliferation and TumorigenesisSemantic proximity Read ↗

Targeting Mutated p53 Dependency in Triple-Negative Breast Cancer Cells Through CDK7 InhibitionSemantic proximity Read ↗

hsa-miR-CHA2, a novel microRNA, exhibits anticancer effects by suppressing cyclin E1 in human non-small cell lung cancer cellsSemantic proximity Read ↗

Silencing of DYRK2 increases cell proliferation but reverses CAM-DR in Non-Hodgkin's Lymphoma.Semantic proximity Read ↗

Abnormal expression of Pygopus 2 correlates with a malignant phenotype in human lung cancer.Semantic proximity Read ↗

Knockdown of PAICS inhibits malignant proliferation of human breast cancer cell linesSemantic proximity Read ↗

<i>CUL7</i> Is a Novel Antiapoptotic OncogeneSemantic proximity Read ↗

FBXO31 is down-regulated and may function as a tumor suppressor in hepatocellular carcinomaSemantic proximity Read ↗

MicroRNA-7 arrests cell cycle in G1 phase by directly targeting CCNE1 in human hepatocellular carcinoma cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.