Article
MicroRNA-7 arrests cell cycle in G1 phase by directly targeting CCNE1 in human hepatocellular carcinoma cells.
Biochemical and biophysical research communications - 17 Jan 2014
Zhang Xiao, Hu Shijie, Zhang Xiang, Wang Lei, Zhang Xiaofang, Yan Bo, Zhao Jing, Yang Angang, Zhang Rui
Abstract excerpt
Growing evidence has demonstrated that the aberrant expression of miRNA is a hallmark of malignancies, indicating the important roles of miRNA in the development and progression of cancer. MiR-7 is considered as a tumor suppressor miRNA in multiple types of cancer. However, the role of miR-7 in human hepatocellular carcinoma (HCC) and its underlying mechanism remain elusive. In this study, we found that...
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