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Article

FBXO31 is down-regulated and may function as a tumor suppressor in hepatocellular carcinoma

23 Jul 2010

Abstract excerpt

The F-box protein family member FBXO31 has rarely been studied in human hepatocellular carcinoma (HCC). This study was designed to investigate the expression profile of FBXO31 in HCC and the possibility that FBXO31 might function as a tumor suppressor in HCC cell lines. We report that FBXO31 is strongly down-regulated in HCC cell lines and specimens. Ectopic expression of FBXO31 inhibited cell proliferation and...

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PMID: 20664978
DOI: 10.3892/or_00000912

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