Article
Polymorphisms in exon 2 of CD1 genes are associated with susceptibility to Guillain-Barré syndrome.
Journal of the neurological sciences - 15 Oct 2016
Liu Hongbo, Xing Yanmeng, Guo Yake, Liu Peidong, Zhang Hui, Xue Bing, Shou Jifei, Qian Juanfeng, Peng Jing, Wang Rui, Gao YiWei, Fang Shuyou
Abstract excerpt
Guillain-Barré syndrome (GBS) is a post-infectious autoimmune peripheral neuropathy. Studies have shown that a T cell-mediated immune response to peripheral nerve is associated with the pathogenesis of GBS. CD1 molecules are MCH-like glycoproteins specialized to capture and present glycolipids to T cells. Polymorphisms of CD1 genes may affect susceptibility to GBS. We investigated the polymorphisms of CD1 genes...
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