Article
Susceptibility to Guillain-Barré syndrome is not associated with CD1A and CD1E gene polymorphisms.
Journal of neuroimmunology - 15 Dec 2008
Kuijf Mark L, Geleijns Karin, Ennaji Noureddine, van Rijs Wouter, van Doorn Pieter A, Jacobs Bart C
Abstract excerpt
Immune responses to microbial glycolipids that cross-react to neural epitopes may trigger the Guillain-Barré syndrome (GBS). CD1 molecules are involved in antigen presentation of glycolipids and variation in CD1 genes was recently reported to confer susceptibility to develop GBS. This hypothesis was tested by comparing single nucleotide polymorphisms (SNPs) of CD1A and CD1E in 312 well defined GBS patients and...
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