Article
Polymorphisms of CD1 genes in chronic dysimmune neuropathies.
Journal of neuroimmunology - 1 May 2007
De Angelis Maria Vittoria, Notturno Francesca, Caporale Christina M, Pace Marta, Uncini Antonino
Abstract excerpt
CD1 are MCH-like glycoproteins specialized in capturing and presenting glycolipid to T cells. Expression of CD1 molecules has been observed on endoneurial machrophages in patients with chronic inflammatory demyelinating polyneuropathy (CIDP) and vasculitis and polymorphisms of CID1A and CD1E genes have been associated with susceptibility to develop Guillain-Barré syndrome. In 46 patients with CIDP, in 13 patients...
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