Article
Susceptibility to Guillain-Barré syndrome is associated to polymorphisms of CD1 genes.
Journal of neuroimmunology - 1 Aug 2006
Caporale Christina M, Papola Franco, Fioroni Maria A, Aureli Anna, Giovannini Armando, Notturno Francesca, Adorno Domenico, Caporale Vincenzo, Uncini Antonino
Abstract excerpt
Guillain-Barré syndrome (GBS) is the prototype of a postinfectious autoimmune neuropathy. Molecular mimicry between glycolipid antigens expressed by an infective antigen such as Campylobacter jejuni and the human peripheral nerve has been hypothesized to be the causative mechanism of GBS. However, only 1/1000 of C. jejuni enteritis develops GBS. This emphasizes the importance of host-related factors in the...
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