Article
Cardiac Calcium ATPase Dimerization Measured by Cross-Linking and Fluorescence Energy Transfer.
Biophysical journal - 20 Sept 2016
Blackwell Daniel J, Zak Taylor J, Robia Seth L
Abstract excerpt
The cardiac sarco/endoplasmic reticulum calcium ATPase (SERCA) establishes the intracellular calcium gradient across the sarcoplasmic reticulum membrane. It has been proposed that SERCA forms homooligomers that increase the catalytic rate of calcium transport. We investigated SERCA dimerization in rabbit left ventricular myocytes using a photoactivatable cross-linker. Western blotting of cross-linked SERCA...
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