Article
Structural dynamics control the MicroRNA maturation pathway.
Nucleic acids research - 16 Nov 2016
Dallaire Paul, Tan Huiping, Szulwach Keith, Ma Christopher, Jin Peng, Major François
Abstract excerpt
MicroRNAs (miRNAs) are crucial gene expression regulators and first-order suspects in the development and progression of many diseases. Comparative analysis of cancer cell expression data highlights many deregulated miRNAs. Low expression of miR-125a was related to poor breast cancer prognosis. Interestingly, a single nucleotide polymorphism (SNP) in miR-125a was located within a minor allele expressed by breast...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.