Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IL-4 and human skin mast cells revisited: reinforcement of a pro-allergic phenotype upon prolonged exposure.

Archives of dermatological research - 1 Nov 2016

Babina Magda, Guhl Sven, Artuc Metin, Zuberbier Torsten

Abstract excerpt

Mast cells (MCs), unique cellular elements of the body, are commonly associated with IgE-mediated reactions and manifestations of Th2-type immunity. A key characteristic of the lineage is its heterogeneity, with subsets displaying significant variation depending on maturation stage, species, tissue, microenvironment and other. Heterogeneity also affects MC responses to extracellular cues. Indeed, IL-4, the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cells, Cultured
Share to Histamine
Share to Hypersensitivity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-4

Share to Mast Cells

Share to Receptors, IgE

Share to Substance P

Source

Identifiers

PMID: 27650274
DOI: 10.1007/s00403-016-1688-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IL-4 and human skin mast cells revisited: reinforcement of a pro-allergic phenotype upon prolonged exposure.PMID 27650274Read ↗

Mast cells: beyond IgE.Semantic proximity Read ↗

The transcriptional program, functional heterogeneity, and clinical targeting of mast cellsSemantic proximity Read ↗

Is it time for a new classification of mast cells? What do we know about mast cell heterogeneity?Semantic proximity Read ↗

The ingenious mast cell: Contemporary insights into mast cell behavior and functionSemantic proximity Read ↗

Hemopoietic cells with features of the mast cell and basophil lineages and their potential role in allergy.Semantic proximity Read ↗

Revisiting the role of the mast cell in asthma.Semantic proximity Read ↗

Utilizing mast cells in a positive manner to overcome inflammatory and allergic diseases.Semantic proximity Read ↗

New perspectives on the origins and heterogeneity of mast cellsSemantic proximity Read ↗

Mast cells as a unique hematopoietic lineage and cell system: From Paul Ehrlich's visions to precision medicine conceptsSemantic proximity Read ↗

Mast cell plasticity and sphingosine-1-phosphate in immunity, inflammation and cancer.Semantic proximity Read ↗

Decoding the intricacies of the mast cell compartment.Semantic proximity Read ↗

T helper cell-licensed mast cells promote inflammatory Th17 cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.