Article
Mast cells: beyond IgE.
The Journal of allergy and clinical immunology - 1 Jan 2003
Boyce Joshua A
Abstract excerpt
Mast cells, historically known for their involvement in type I hypersensitivity, also serve critical protective and homeostatic functions. They directly recognize the products of bacterial infection through several surface receptor proteins, releasing proteases, cytokines, and eicosanoid mediators that recruit neutrophils, limit the spread of bacterial infection, and facilitate subsequent tissue repair. In vitro...
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