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Article

SMN - A chaperone for nuclear RNP social occasions?

20 Sept 2016

Abstract excerpt

Survival Motor Neuron (SMN) protein localizes to both the nucleus and the cytoplasm. Cytoplasmic SMN is diffusely localized in large oligomeric complexes with core member proteins, called Gemins. Biochemical and cell biological studies have demonstrated that the SMN complex is required for the cytoplasmic assembly and nuclear transport of Sm-class ribonucleoproteins (RNPs). Nuclear SMN accumulates with...

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PMID: 27648855
DOI: 10.1080/15476286.2016.1236168

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