Article
The regulation of soluble receptor for AGEs contributes to carbonyl stress in schizophrenia.
Biochemical and biophysical research communications - 21 Oct 2016
Miyashita Mitsuhiro, Watanabe Takuo, Ichikawa Tomoe, Toriumi Kazuya, Horiuchi Yasue, Kobori Akiko, Kushima Itaru, Hashimoto Ryota, Fukumoto Motoyuki, Koike Shinsuke, Ujike Hiroshi, Arinami Tadao, Tatebayashi Yoshitaka, Kasai Kiyoto, Takeda Masatoshi, Ozaki Norio, Okazaki Yuji, Yoshikawa Takeo, Amano Naoji, Washizuka Shinsuke, Yamamoto Hiroshi, Miyata Toshio, Itokawa Masanari, Yamamoto Yasuhiko, Arai Makoto
Abstract excerpt
Our previous study showed that enhanced carbonyl stress is closely related to schizophrenia. The endogenous secretory receptor for advanced glycation end-products (esRAGE) is a splice variant of the AGER gene and is one of the soluble forms of RAGE. esRAGE is considered to be a key molecule for alleviating the burden of carbonyl stress by entrapping advanced glycation end-products (AGEs). In the current study, we...
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