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Article

Age and genetic determinants of variation of circulating levels of the receptor for advanced glycation end products (RAGE) in the general human population.

Mechanisms of ageing and development - 1 Jan 2015

Prakash Jai, Pichchadze Guram, Trofimov Svetlana, Livshits Gregory

Abstract excerpt

In stark contrast to many other blood biomarkers, including a variety of inflammatory cytokines, the main factors affecting sRAGE variation in the general human population are virtually unknown. We examined the contribution of age, body composition, and putative genetic sources to the interindividual variation of sRAGE. Its plasma levels were measured in 1557 apparently healthy individuals from 359 nuclear...

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PMID: 25681682
DOI: 10.1016/j.mad.2015.01.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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