Article
Analysis of novel alleles of brother of tout-velu, the drosophila ortholog of human EXTL3 using a newly developed FRT42D ovoD chromosome.
Genesis (New York, N.Y. : 2000) - 1 Nov 2016
Lujan Ernesto, Bornemann Douglas J, Rottig Carmen, Bayless Brian A, Stocker Hugo, Hafen Ernst, Arora Kavita, Warrior Rahul
Abstract excerpt
The FLP/FRT system permits rapid phenotypic screening of homozygous lethal mutations in the context of a viable mosaic fly. Combining this system with ovoD dominant female-sterile transgenes enables efficient production of embryos derived from mutant germline clones lacking maternal contribution from a gene of interest. Two distinct sets of FRT chromosomes, carrying either the mini-white (w + mW.hs ), or rosy...
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