Article
Production of dominant female sterility in Drosophila melanogaster by insertion of the ovoD1 allele on autosomes: use of transformed strains to generate germline mosaics.
Mechanisms of development - 1 Feb 1994
Mével-Ninio M, Guénal I, Limbourg-Bouchon B
Abstract excerpt
We have cloned a 7 kb genomic fragment containing the dominant female-sterile mutation ovoD1. This fragment confers to transgenic females a sterility phenotype, the severity of which depends both on the genetic background and the ratio of ovoD1 product to ovo+ product. Females containing two copi...
Topics
- Alleles
- Animals
- Animals, Genetically Modified
- Chromosomes
- Drosophila melanogaster
- Female
- Genes, Dominant
- Infertility, Female
- Mosaicism
- Phenotype
- Recombination, Genetic
- Transformation, Genetic