Article
Molecular or Metabolic Reprograming: What Triggers Tumor Subtypes?
Cancer research - 15 Sept 2016
Eason Katherine, Sadanandam Anguraj
Abstract excerpt
Tumor heterogeneity is reflected and influenced by genetic, epigenetic, and metabolic differences in cancer cells and their interactions with a complex microenvironment. This heterogeneity has resulted in the stratification of tumors into subtypes, mainly based on cancer-specific genomic or transcriptomic profiles. Subtyping can lead to biomarker identification for personalized diagnosis and therapy, but...
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