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Article

miR-196a Ameliorates Cytotoxicity and Cellular Phenotype in Transgenic Huntington's Disease Monkey Neural Cells.

PloS one - 1 Jan 2016

Kunkanjanawan Tanut, Carter Richard L, Prucha Melinda S, Yang Jinjing, Parnpai Rangsun, Chan Anthony W S

Abstract excerpt

Huntington's disease (HD) is an inherited neurodegenerative disorder caused by the expansion of polyglutamine (polyQ) tract that leads to motor, cognitive and psychiatric impairment. Currently there is no cure for HD. A transgenic HD nonhuman primate (HD-NHP) model was developed with progressive development of clinical and pathological features similar to human HD, which suggested the potential preclinical...

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PMID: 27631085
DOI: 10.1371/journal.pone.0162788
PMCID: PMC5025087

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PGC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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