Article
The Potential Regulatory Mechanisms of miR-196a in Huntington's Disease through Bioinformatic Analyses.
PloS one - 1 Jan 2015
Fu Mu-Hui, Li Chia-Ling, Lin Hsiu-Lien, Tsai Shaw-Jeng, Lai Yen-Yu, Chang Yu-Fan, Cheng Pei-Hsun, Chen Chuan-Mu, Yang Shang-Hsun
Abstract excerpt
High throughput screening is a powerful tool to identify the potential candidate molecules involved during disease progression. However, analysis of complicated data is one of the most challenging steps on the way to obtaining useful results from this approach. Previously, we showed that a specific miRNA, miR-196a, could ameliorate the pathological phenotypes of Huntington's disease (HD) in different models, and...
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