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Article

Hypomethylation of Interleukin-6 Promoter is Associated with the Risk of Coronary Heart Disease.

Arquivos brasileiros de cardiologia - 1 Aug 2016

Zuo Hong-Peng, Guo Ying-Yu, Che Lin, Wu Xian-Zheng

Abstract excerpt

BACKGROUND: Interleukin-6 (IL-6) is implicated in the pathogenesis of coronary heart disease (CHD), and IL-6 expression has associated with reduced DNA methylation of its gene promoter. However, there are no data on IL-6 promoter methylation and the risk of CHD. OBJECTIVE: To examine whether IL-6 promoter methylation measured in blood leukocyte DNA is associated with CHD risk. METHODS: A total of 212 cases with...

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Identifiers

PMID: 27627640
DOI: 10.5935/abc.20160124
PMCID: PMC5074066

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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