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Article

Mutational burdens and evolutionary ages of thyroid follicular adenoma are comparable to those of follicular carcinoma.

Oncotarget - 25 Oct 2016

Jung Seung-Hyun, Kim Min Sung, Jung Chan Kwon, Park Hyun-Chun, Kim So Youn, Liu Jieying, Bae Ja-Seong, Lee Sung Hak, Kim Tae-Min, Lee Sug Hyung, Chung Yeun-Jun

Abstract excerpt

Follicular thyroid adenoma (FTA) precedes follicular thyroid carcinoma (FTC) by definition with a favorable prognosis compared to FTC. However, the genetic mechanism of FTA to FTC progression remains unknown. For this, it is required to disclose FTA and FTC genomes in mutational and evolutionary perspectives. We performed whole-exome sequencing and copy number profiling of 14 FTAs and 13 FTCs, which exhibited...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27626165
DOI: 10.18632/oncotarget.11922
PMCID: PMC5342504

Genes

BRAF
BRIP1
CNOT1
HRAS
NRAS
SPOP
STAG2
TCF12
TSHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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