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Article

Somatic mutation profiling of follicular thyroid cancer by next generation sequencing.

Molecular and cellular endocrinology - 15 Sept 2016

Swierniak Michal, Pfeifer Aleksandra, Stokowy Tomasz, Rusinek Dagmara, Chekan Mykola, Lange Dariusz, Krajewska Jolanta, Oczko-Wojciechowska Małgorzata, Czarniecka Agnieszka, Jarzab Michal, Jarzab Barbara, Wojtas Bartosz

Abstract excerpt

The molecular etiology of follicular thyroid tumors is largely unknown, rendering the diagnostics of these tumors challenging. The somatic alterations present in these tumors apart from RAS gene mutations and PAX8/PPARG translocations are not well described. To evaluate the profile of somatic alteration in follicular thyroid tumors, a total of 82 thyroid tissue samples derived from 48 patients were subjected to...

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Share to Adenocarcinoma, Follicular
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27283500
DOI: 10.1016/j.mce.2016.06.007

Genes

FLI1
ALK
CHEK2
JAK3
MDM2
MITF
NCOA1
NCOA2
NSD1
PAX8
PPARG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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