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Article

Partners in crime: Proteins implicated in RNA repeat expansion diseases

28 Feb 2022

Abstract excerpt

Abstract Short tandem repeats are repetitive nucleotide sequences robustly distributed in the human genome. Their expansion underlies the pathogenesis of multiple neurological disorders, including Huntington's disease, amyotrophic lateral sclerosis, and frontotemporal dementia, fragile X‐associated tremor/ataxia syndrome, and myotonic dystrophies, known as repeat expansion disorders (REDs). Several molecular...

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PMID: 35229468
DOI: 10.1002/wrna.1709

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