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Article

Menopause: Genome stability as new paradigm.

Maturitas - 1 Oct 2016

Laven Joop S E, Visser Jenny A, Uitterlinden Andre G, Vermeij Wilbert P, Hoeijmakers Jan H J

Abstract excerpt

Menopause is defined as the age-dependent permanent cessation of menstruation and ovulation due to ovarian failure. Menopause occurs on average around the age of 51 years. Recent genome-wide association studies (GWAS) have identified over 44 genetic variants that are associated with age of onset of natural menopause. Genes linked with menopause can be classified into three major groups: genes implicated in genome...

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Identifiers

PMID: 27621233
DOI: 10.1016/j.maturitas.2016.07.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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