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Article

Mutational analysis of TP53 gene in Tunisian familial hematological malignancies and sporadic acute leukemia cases.

Familial cancer - 1 Jan 2017

Hamadou Walid Sabri, Besbes Sawsen, Bourdon Violaine, Youssef Yosra Ben, Laatiri Mohamed Adnène, Noguchi Testsuro, Khélif Abderrahim, Sobol Hagay, Soua Zohra

Abstract excerpt

Mutations are responsible for familial cancer syndromes which account for approximately 5-10 % of all types of cancers. Familial cancers are often caused by genetic alterations occurring either in tumor suppressor or genomic stability genes such as TP53. In this study, we have analyzed the TP53 gene by direct sequencing approach, in a panel of 18 Tunisian familial hematological malignancies cases including...

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PMID: 27619989
DOI: 10.1007/s10689-016-9931-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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