Article
Leishmania infantum antigens modulate memory cell subsets of liver resident T lymphocyte.
Immunobiology - 1 Feb 2017
Rodrigues A, Claro M, Alexandre-Pires G, Santos-Mateus D, Martins C, Valério-Bolas A, Rafael-Fernandes M, Pereira M A, Pereira da Fonseca I, Tomás A M, Santos-Gomes G
Abstract excerpt
In the recent years, the liver has been recognized as an important immune organ with major regulatory functions and immune memory, adding to the well-described vital metabolic functions. There are evidences from experimental infections performed with visceral Leishmania species that immune responses to parasite infection can be organ-specific. The liver is the compartment of acute resolving infection, with...
Topics
- Animals
- Antigens, Protozoan
- Biomarkers
- Disease Models, Animal
- Host-Parasite Interactions
- Immunologic Memory
- Immunophenotyping
- Leishmania infantum
- Leishmaniasis, Visceral
- Leukocytes
- Liver
- Lymphocyte Activation
- Mice