Article
Relationship of microRNA 616 gene polymorphism with prognosis of patients with premature coronary artery disease.
International journal of clinical pharmacology and therapeutics - 1 Nov 2016
Zhang Yan, Wang Shijie, Li Yongqin, Zhang Chunyan, Xue Jiahong, Wu Xiaosan, Wang Congxia
Abstract excerpt
OBJECTIVE: To investigate the relationship of microRNA 616 (has-miR-616) single nucleotide polymorphisms (SNPs) and its target gene paraoxonase 1 (PON 1) with the prognosis of patients with premature coronary artery disease (pCAD). METHODS: 266 pCAD cases in the case group and 300 cases in the control group were collected. Using the polymorphism method of polymerase chain reaction and restriction fragment length,...
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