Article
Polymorphisms of miRNAs genes are associated with the risk and prognosis of coronary artery disease.
Clinical research in cardiology : official journal of the German Cardiac Society - 1 Apr 2012
Zhi Hong, Wang Lina, Ma Genshan, Ye Xingzhou, Yu Xiaojin, Zhu Yi, Zhang Yu, Zhang Jiaju, Wang Bei
Abstract excerpt
BACKGROUND: MicroRNAs (miRNAs) are small, single-stranded, non-protein-coding RNAs of about 22 nucleotides. miRNA molecules have been identified that plays key roles in a broad range of physiologic and pathologic processes. Polymorphisms in the corresponding sequence space are likely to make a significant contribution to phenotypic variation. METHODS AND RESULTS: To assess the variations of rs11614913 T → C in...
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