Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of HA and NA glycosylation pattern changes on the transmission of avian influenza A(H7N9) virus in guinea pigs.

Biochemical and biophysical research communications - 14 Oct 2016

Park Sehee, Lee Ilseob, Kim Jin Il, Bae Joon-Yong, Yoo Kirim, Kim Juwon, Nam Misun, Park Miso, Yun Soo-Hyeon, Cho Woo In, Kim Yeong-Su, Ko Yun Young, Park Man-Seong

Abstract excerpt

Avian influenza H7N9 virus has posed a concern of potential human-to-human transmission by resulting in seasonal virus-like human infection cases. To address the issue of sustained human infection with the H7N9 virus, here we investigated the effects of hemagglutinin (HA) and neuraminidase (NA) N-linked glycosylation (NLG) patterns on influenza virus transmission in a guinea pig model. Based on the NLG signatures...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Birds
Share to Guinea Pigs

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hemagglutinin Glycoproteins, Influenza Virus

Share to Influenza A Virus, H7N9 Subtype

Share to Influenza, Human

Share to Influenza in Birds

Share to Neuraminidase

Share to Orthomyxoviridae Infections

Source

Identifiers

PMID: 27613087
DOI: 10.1016/j.bbrc.2016.09.024

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of HA and NA glycosylation pattern changes on the transmission of avian influenza A(H7N9) virus in guinea pigs.PMID 27613087Read ↗

Analysis of Recombinant H7N9 Wild-Type and Mutant Viruses in Pigs Shows that the Q226L Mutation in HA Is Important for TransmissionSemantic proximity Read ↗

Identification of amino acids in HA and PB2 critical for the transmission of H5N1 avian influenza viruses in a mammalian host.Semantic proximity Read ↗

H5N1 hybrid viruses bearing 2009/H1N1 virus genes transmit in guinea pigs by respiratory droplet.Semantic proximity Read ↗

A Single-Amino-Acid Substitution at Position 225 in Hemagglutinin Alters the Transmissibility of Eurasian Avian-Like H1N1 Swine Influenza Virus in Guinea PigsSemantic proximity Read ↗

Novel H7N9 Influenza Virus Shows Low Infectious Dose, High Growth Rate, and Efficient Contact Transmission in the Guinea Pig ModelSemantic proximity Read ↗

Adaptation of H9N2 AIV in guinea pigs enables efficient transmission by direct contact and inefficient transmission by respiratory dropletsSemantic proximity Read ↗

Identifying novel amino acid substitutions of hemagglutinin involved in virulence enhancement in H7N9 virus strains.Semantic proximity Read ↗

Identification of Key Amino Acids in the PB2 and M1 Proteins of H7N9 Influenza Virus That Affect Its Transmission in Guinea PigsSemantic proximity Read ↗

Transmission of influenza virus in a mammalian host is increased by PB2 amino acids 627K or 627E/701N.Semantic proximity Read ↗

The neuraminidase and matrix genes of the 2009 pandemic influenza H1N1 virus cooperate functionally to facilitate efficient replication and transmissibility in pigsSemantic proximity Read ↗

Glycosylation on hemagglutinin affects the virulence and pathogenicity of pandemic H1N1/2009 influenza A virus in mice.Semantic proximity Read ↗

N-linked glycosylation at site 158 of the HA protein of H5N6 highly pathogenic avian influenza virus is important for viral biological properties and host immune responsesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.