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Article

Identification of amino acids in HA and PB2 critical for the transmission of H5N1 avian influenza viruses in a mammalian host.

PLoS pathogens - 1 Dec 2009

Gao Yuwei, Zhang Ying, Shinya Kyoko, Deng Guohua, Jiang Yongping, Li Zejun, Guan Yuntao, Tian Guobin, Li Yanbing, Shi Jianzhong, Liu Liling, Zeng Xianying, Bu Zhigao, Xia Xianzhu, Kawaoka Yoshihiro, Chen Hualan

Abstract excerpt

Since 2003, H5N1 influenza viruses have caused over 400 known cases of human infection with a mortality rate greater than 60%. Most of these cases resulted from direct contact with virus-contaminated poultry or poultry products. Although only limited human-to-human transmission has been reported...

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Identifiers

PMID: 20041223
DOI: 10.1371/journal.ppat.1000709
PMCID: PMC2791199

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20041223-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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