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Article

Transmission of influenza virus in a mammalian host is increased by PB2 amino acids 627K or 627E/701N.

PLoS pathogens - 1 Jan 2009

Steel John, Lowen Anice C, Mubareka Samira, Palese Peter

Abstract excerpt

Since 2003, more than 380 cases of H5N1 influenza virus infection of humans have been reported. Although the resultant disease in these cases was often severe or fatal, transmission of avian influenza viruses between humans is rare. The precise nature of the barrier blocking human-to-human spread is unknown. It is clear, however, that efficient human-to-human transmission of an antigenically novel influenza virus...

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Identifiers

PMID: 19119420
DOI: 10.1371/journal.ppat.1000252
PMCID: PMC2603332

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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