Article
Susceptibility for cigarette smoke-induced DAMP release and DAMP-induced inflammation in COPD.
American journal of physiology. Lung cellular and molecular physiology - 1 Nov 2016
Pouwels Simon D, Hesse Laura, Faiz Alen, Lubbers Jaap, Bodha Priya K, Ten Hacken Nick H T, van Oosterhout Antoon J M, Nawijn Martijn C, Heijink Irene H
Abstract excerpt
Cigarette smoke (CS) exposure is a major risk factor for chronic obstructive pulmonary disease (COPD). We investigated whether CS-induced damage-associated molecular pattern (DAMP) release or DAMP-mediated inflammation contributes to susceptibility for COPD. Samples, including bronchial brushings, were collected from young and old individuals, susceptible and nonsusceptible for the development of COPD, before and...
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