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Article

Little Cigars are More Toxic than Cigarettes and Uniquely Change the Airway Gene and Protein Expression

27 Apr 2017

Abstract excerpt

Little cigars (LCs) are regulated differently than cigarettes, allowing them to be potentially targeted at youth/young adults. We exposed human bronchial epithelial cultures (HBECs) to air or whole tobacco smoke from cigarettes vs. LCs. Chronic smoke exposure increased the number of dead cells, lactate dehydrogenase release, and interleukin-8 (IL-8) secretion and decreased apical cilia, cystic fibrosis...

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Share to Chronic Obstructive Pulmonary Disease (COPD) Research
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PMID: 28447619
DOI: 10.1038/srep46239

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