Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic background of high myopia in children.

PloS one - 1 Jan 2024

Šenk Urh, Čižman Bernard, Writzl Karin, Tekavčič Pompe Manca

Abstract excerpt

OBJECTIVE: High myopia is a significant risk factor for irreversible vision loss and can occur in isolation or as a component of various syndromes. However, the genetic basis of early-onset high myopia remains poorly understood. We aimed to identify the causative genetic variants for high myopia in a cohort of Slovenian children. METHODS: The study included children referred to a tertiary paediatric ophthalmology...

Topics

Join the communities discussing this publication.

Adolescent
Child
Child, Preschool
Exome Sequencing
Genetic Background
Genetic Testing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Open in PubMed Open full text

Identifiers

PMID: 39495751
DOI: 10.1371/journal.pone.0313121
PMCID: PMC11534203

Genes

ARR3
CACNA1F
NDP
RP2
RPGR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic background of high myopia in children.PMID 39495751Read ↗

IMI – Myopia Genetics ReportSemantic proximity Read ↗

[Features of genetic mutations in children with high myopia combined with peripheral retinal degenerations].Semantic proximity Read ↗

Whole exome sequencing of known eye genes reveals genetic causes for high myopiaSemantic proximity Read ↗

Clinical and genetic risk factors underlying severe consequence identified in 75 families with unilateral high myopia.Semantic proximity Read ↗

IMI-Myopia Genetics Report.Semantic proximity Read ↗

Analysis of gene mutation spectrum for early-onset high myopia based on whole-exome sequencing.Semantic proximity Read ↗

Molecular Genetics of Human Myopia: An UpdateSemantic proximity Read ↗

Update on the epidemiology and genetics of myopic refractive errorSemantic proximity Read ↗

Whole-exome sequencing on 6215 school-aged children reveals the importance of genetic testing in high myopiaSemantic proximity Read ↗

When do myopia genes have their effect? Comparison of genetic risks between children and adults.Semantic proximity Read ↗

Myopia Genetics and HereditySemantic proximity Read ↗

Trio-based whole-exome sequencing reveals mutations in early-onset high myopia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.