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Article

HIV Protease Inhibitors Apoptotic Effect in SH-SY5Y Neuronal Cell Line

1 Jan 2016

Abstract excerpt

BACKGROUND: Prophylactic treatment regimens to prevent mother-to-child HIV transmission include protease inhibitors Lopinavir and Ritonavir. Lopinavir and Ritonavir have been reported to be able to induce intracellular oxidative stress in diverse cellular models, however scarce informations are available about protease inhibitor effects of in the central nervous system (CNS). In our study we evaluated the impact...

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PMID: 27607424
DOI: 10.1159/000447849

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