Article
DNA methylation mediated up-regulation of<i>TERRA</i>non-coding RNA is coincident with elongated telomeres in the human placenta
7 Sept 2016
Abstract excerpt
STUDY QUESTION: What factors regulate elongated telomere length in the human placenta? SUMMARY ANSWER: Hypomethylation of TERRA promoters in the human placenta is associated with high TERRA expression, however, no clear mechanistic link between these phenomena and elongated telomere length in the human placenta was found. WHAT IS KNOWN ALREADY: Human placenta tissue and trophoblasts show longer telomere lengths...
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